Clinical and Epidemiological Investigation Center (CIEC) / Competence centers / CRP-Santé

Clinical and Epidemiological Investigation Center (CIEC)

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Services
Activities
Investigators
Team

The main objectives of the CIEC are to promote clinical research and to assist and support clinical research projects in Luxembourg. Therefore the CIEC may provide any kind of logistic support to hospitals or physicians interested in clinical trials. The CIEC is also a contact partner for the pharmaceutical industries interested in conducting clinical trials in Luxembourg.

In addition, the CIEC is aiming at developing a national clinical research network including clinicians and physicians in various medical fields in order to react in a timely manner to demands emanating from potential sponsors.

Furthermore the CIEC is an infrastructure intended to prepare and realize, partially or totally, clinical research projects based on patients or healthy volunteers, in the respect of Good Clinical Practice (ICH-GCP) and Quality Assurance. The CIEC is therefore also an opportunity for internal and external research teams to consolidate fundamental and experimental findings by a clinical research study in healthy volunteers or patients. Thus CIEC acts at the interface between fundamental and clinical research, i.e. translational research and helps providing new scientific and medical knowledge.

Finally, the CIEC is striving to ensure respect of patient rights and patient data privacy, while offering the opportunity to access new and innovative therapeutic approaches that wouldn’t be accessible otherwise. The CIEC personnel is trained and dedicated to offer the best patient information and support all along the clinical trial process.

Visit our website dedicated to Clinical Research in Luxembourg, Luxclin: https://www.luxclin.lu /

History

September 2008 : Creation of the Clinical and Epidemiological Investigation Centre of Luxembourg
Friday 25 September 2009 : Clinical Research Day - First edition – Luxembourg

145 patients enrolled in total in 14 trials covering 5 different therapeutic fields.

3 ongoing academic trials:
A public health study (nutrition and cardiovascular disease) in collaboration with the Neurology department at Centre Hospitalier de Luxembourg (CHL), counting 40 patients included and followed up over a period of 4 months.
Further CIEC is supporting the IBBL (Integrated BioBank of Luxemburg) in a Lung Cancer Study in association with the CHL in means of patients’ clinical data as well as tissue, saliva and blood collections. The data and samples of 17 patients have been collected so far.
Finally a single center radio-diagnostic study using FNa18 in orthopedic diseases is in preparation in collaboration with CHL.
I5 clinical trials sponsored by Pharma Industry were initiated in Luxembourg: 3 oncology studies, 1 cardiovascular and 1 endocrinology trial, all ongoing and recruiting.
The coordination and logistic of 5 ongoing clinical trials at the CHL was taken over by the CIEC, including 2 Investigator Initiated Trials (IIT) run in collaboration with Belgian University Hospitals.

Ongoing projects

Publications

Presentations

Assistance in developing individual clinical research projects
Submission of research projects to “Comité National d’Ethique de Recherche ”, “Commission Nationale de Protection des Données ” and/or Ministry of Health (* permission to use pending)
Logistic support for conducting clinical trials including redaction of protocols and case report forms, contracting insurance, elaborating financial conventions, data monitoring and collection, data base set up, statistical analysis, exploitation and publication of results
Support patient recruitment in trials
Standard Operating Procedures (SOP): The entire CIEC Team is working according to own CIEC SOP Manual based on ICH – GCP
Management of patient visits: Individual patient consultations at CIEC (2 fully equipped patient consultation rooms)
Clinical Trials