To provide its expertise during the preparation of studies in order to determine the design best suited to the research questions. To define the data management methods which guarantee the quality of the results. Supporting teams in the handling of data.
Methodology and Statistics
- The Competence Center for Methodology and Statistics (CCMS) was established in March 2010 in order to meet the methodological and statistical needs of the Department of Public Health and to support the other research departments and laboratories within CRP-Santé. The CCMS further aims to develop contractual public health management and data handling activities for other national and international bodies.
- CCMS also promotes the production of high quality data, which is necessary if the subsequent statistical analysis is to be informative. Expertise is provided during the preparation of studies in order to determine the best suitable design for the research questions asked. Data management methods are also defined, guaranteeing the highest quality of statistical results for each study. For this purpose the Capture System software covers all areas of data management and provides a secure location for clinical data, user rights, and profiles, along with password protection. A full audit trail is put in place for each new study.
- Courses have been provided in statistics in nursing (IFSI), clinical research (IUT), meta-analysis (Roche), and statistical issues in drug development (Royal Statistical Society). A series of statistics notes designed to help medical researchers is in preparation.
As a former Professor of Statistics at the University of Glasgow ; Professor of Pharmaceutical and Health Statistics at University College London ; statistician with the National Health Service in England , and within the Swiss pharmaceutical industry , Prof. Senn brings to CRP-Santé his extensive experience in both academia and industry. Prof. Senn is recognized worldwide for his studies in statistical methodology applied to drug development.
He has been the recipient of national and international awards, including the 1st George C Challis award for Biostatistics at the University of Florida, and the Bradford Hill Medal of the Royal Statistical Society. He is the author of the monographs Cross-over Trials in Clinical Research (1993, 2002), Statistical Issues in Drug Development (1997, 2007) and Dicing with Death (2003), as well as numerous scientific articles published in internationally recognized, peer-reviewed journals.
Prof. Senn is a Fellow of the Royal Society of Edinburgh and an honorary life member of Statisticians in the Pharmaceutical Industry (PSI) and the International Society for Clinical Biostatistics (ISCB) and has an honorary chair in statistics at University College London.
The activities of the CCMS include:
- Methodological advice to define research project designs
- Organization of study data in tandem with project managers
- Statistical support for project managers
- Collaboration with external scientists working in fields of mutual interest
- Providing statistical editing support for scientific publications
- Monitoring, editing and updating data management procedures according to international recommendations
- Teaching courses in statistics for healthcare researchers
- Developing and researching statistical methodology of practical relevance to healthcare research