EVENTS
07/05/2010 Proteomics based therapeutic target discovery in oncology
07/05/2010
- Speaker: Yeoun Jin Kim, PhD, Bristol-Myers Squibb Company
- Language: English
- Location: BAM - 84 Val Fleuri - Strassen
- Contact: andre.steinmetz@crp-sante.lu
Monoclonal antibody therapeutics is one of the fastest growing areas in the pharmaceutical industry because of the advantages including higher safety, efficacy and lower development cost. Discovery of novel target proteins for such therapy can provide great opportunities to improve therapeutic strategies for unmet medical needs. In this seminar, proteomic discovery platform for identifying potential oncology target proteins will be discussed with the colorectal cancer (CRC) program as an example. This includes quantitative measurement of the expression level of cell surface proteins and identification of the proteins expressed exclusively on CRC cells. Biological validation of the potential target proteins identified by this platform will be also discussed.
This work is based on the proteomics platform of Celera.