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2011 - 07 - 25 Simone Alt defended his PhD thesis at the University of Trier, Germany
Department of Immunology (LNSI). Simone Alt recently defended her Ph.D. thesis (magna cum laude) at the University of Trier, Germany. The title of her PhD thesis is “The glucocorticoid receptor: transcriptional regulation and epigenetic programming” .
Simone Alt has written or co-authored 3 publications, two other publication are submitted or in preparation. She has given numerous oral presentations, both as department seminars and at national and international meetings. Simone participated actively in the organisation of the Autumn School in Psychobiology 2009 in Luxembourg, which was part of the successful series of Trier Summer Schools and of the DFG- and NWO-sponsored International Research Training Group on 'Psychoneuroendocrinology of Stress: from Molecules and Genes to Affect and Cognition', which is a joined venture of Melly Oitzl's & Ron de Kloet's Leiden research group and the psychobiology research groups in Trier and Luxembourg.
Since May 2011 Simone Alt is programme manager for life sciences at the EU service office of the Saarland University in Saarbrücken. This gives us the opportunity to stay in contact with Simone and to collaborate in the future.
Publications list of Simone Alt during her PhD at the Department of Immunology
MD Klok, SR Alt, AJ Irurzun Lafitte, JD Turner, EA Lakke, I Huitinga, CP Muller, FG Zitman, ER de Kloet, RH Derijk. Decreased expression of mineralocorticoid receptor mRNA and its splice variants in postmortem brain regions of patients with major depressive disorder. J Psychiatric Res 45, 871-878, 2011.
JD Turner, SR Alt, L Cao, S Vernocchi, S Trifonova, N Battello, CP Muller. Transcriptional control of the glucocorticoid receptor: CpG islands, epigenetics and more. Biochem Pharmacol 80, 1860-1868, 2010.
SR Alt, JD Turner, MD Klok, OC Meijer, EA Lakke, RH de Rijk, CP Muller. Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed. Psychoneuroendocrinology 35, 544-556, 2010.
SR Alt, L Cao, SC Leija, SB Mériaux, OC Meijer, JD Turner, CP Muller. Transcriptional regulation of the glucocorticoid receptor transcript 1F: NGFI-A and E2F1? Submitted.