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Scope

Our fields of interest range from basic research to contract R&D for the diagnostic and vaccine industry.

  • Immunology and genetic/antigenetic diversity of old and new emerging viruses: relevance for detection, vaccination, pathogenicity, drug resistance, development of new treatment strategies
  • Development of immune-preventive strategies against infectious agents and against environmental risk factors, such as carcinogens.
  • Crosstalk between the immune system and the neuroendocrine system in particular under stress: gene structure, the transcriptional and translational regulation of nuclear receptors, such as the glucocorticoid receptor as the main stress response mediator.
  • Perinatal programming and epigenetics of the immune system.
  • Proteomics studies using 2D DIGE technology paired with MALDI-TOF mass spectrometry and LC-MS in the above areas and other fields in collaboration.

Contact

Department of Immunology
Head of Research Unit: Prof. Dr. Claude P. Muller
Laboratoire National de Santé
20A, rue Auguste Lumière, L-1950 Luxembourg
Tel.: +352 49 06 04 220
Fax: +352 49 06 86
E-mail: claude.muller@crp-sante.lu

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PRESENTATION

The Department of Immunology is an institution of the Centre de Recherche Public de la Santé (CRP-Santé) and the Laboratoire National de Santé (LNS). The department was de facto created in 1992. Since then it has gradually expanded its scientific activities with the support of competitive research grants from national (CRP-Santé, Ministère de la Recherche, Ministère de la Santé, Ministère de la Coopération, Fonds National de la Recherche, Foundations) and international (the European Union DGXII and DGXIII, the World Health Organisation, the Deutsche Forschungsgesellschaft DFG, diagnostic and vaccine industry) sources.
Academically, the department is affiliated with several universities of the Greater Region: the University of Homburg/Saarland, the University of Trier and the University of Nancy. The department is the WHO collaborating centre for reference and research on measles infections, a WHO regional reference laboratory for measles and rubella for 24 European countries and the National Reference Laboratory for Measles and Rubella.
Today, the department of Immunology has grown to a staff of about 35 scientists, engineers, technicians, PhD and MD students, as well as undergraduate students and support staff. The department is one of the most productive biomedical research groups in Luxembourg, with about 15-20 peer-reviewed international scientific publications per year, and 60-80 contributions to scientific conferences and invited oral presentations per year.
More than 50 PhD and MD students have been or are trained at the department of Immunology.
The department has a unique network of international collaborations in Europe and beyond. Our international scientific partners benefit from our training and capacity building program.

TECHNOLOGIES

New technologies are the driving engine of innovation and development. Top of the line equipment and a wide range of state-of-the-art technologies are available, providing an optimal environment for research and the training of students and visiting scientists.

Available techniques  at the Department of Immunology.

SPECIAL HIGHLIGHTS

COLLABORATIONS

The Department has many collaborations with academic and research institutions in Luxembourg , Europe and worldwide  and coordinates or is a member of several networks .