The laboratory of Retrovirology performs fundamental and applied research in the field of chronic viral infections (HIV, HBV, HCV). The activities of the laboratory focus on two research domains, which interact closely: immuno-virology and clinical virology.
Laboratory of Retrovirology
Chronic viral infections caused by HIV and HCV are an ever-growing public health problem in Luxembourg as in the rest of the world. The Laboratory of Retrovirology was founded in 1989 as the national reference laboratory for HIV and is working in close relationship with the National Department of Infectious Diseases. Besides routine clinical activities financed by the Ministry of Health, the Laboratory of Retrovirology has developed clinically oriented biomedical research in the field of chronic viral infections. The activities of the laboratory focus on two research domains, which interact closely: immuno-virology and clinical virology.
Our bioinformatics team has developed tools to support HIV research projects:
- the automated sequence analysis software ART-A for HIV
and developed within the ART-A network project
- the HIV subtyping tool COMET
Our HIV research is supported by grants from the "Fondation Recherche sur le SiDA". Tax-deducible donations to the foundation can be made on the bank accounts:
BIC CCPLLULL IBAN LU88 1111 0877 7890 0000
BIC BGLLLULL IBAN LU92 0030 4314 3109 0000
BIC BILLLULL IBAN LU20 0021 1072 3090 0000,
under the label "support for the Laboratory of Retrovirology/CRP-Santé".
1. Immuno-virology research unit
One of the objectives of the immuno-virology unit is the study of the viral and host factors involved in virus entry and replication to unravel the complex interplay between virus and cells and to identify new diagnostic and therapeutic lead compounds. A second objective is the study of humoral immune responses during HIV infection aiming to obtain better understanding of its impact on the B cell immune repertoire and to characterize the role of the neutralizing and non-neutralizing antibodies. The identification of HIV specific epitopes/mimotopes could lead to the development of new immunogens for a multi-epitope vaccine.
2. Clinical virology research unit
The research projects of the clinical virology unit are focused on transmission networks and dynamics of epidemics caused by HIV and HCV in Luxembourg as well as drug resistance to antiretroviral therapy (HIV) and to Direct Acting Antivirals (HCV). These activities are being developed at the international level through our implication within the ESAR (European Society for Antiviral Resistance) network . In addition, our activities focused on clinical implications of viral and host factors involved in HIV-1 entry and collaborations with African countries.
Associate Head of Laboratory :
Current Team Members :
Function : Technician
Phone : +352 26970-212
Fax : +352 26970-390
Email : nadia.beaupain@crp-sante.lu
Function : Researcher
Phone : +352 26970-336
Fax : +352 26970-390
Email : andy.chevigne@crp-sante.lu
Function : Technician
Phone : +352 26970-225
Fax : +352 26970-390
Email : manuel.counson@crp-sante.lu
Function : Researcher
Phone : +352 26970-211
Fax : +352 26970-390
Email : sylvie.delhalle@crp-sante.lu
Function : Post-doc Researcher
Phone : +352 26970-211
Fax : +352 26970-390
Email : virginie.fievez@crp-sante.lu
Function : Research Engineer
Phone : +352 26970-262
Fax : +352 26970-226
Email : aurelie.fischer@crp-sante.lu
Function : IT Specialist
Phone : +352 26970-217
Fax : +352 26970-390
Email : laurence.guillorit@crp-sante.lu
Function : Research Engineer
Phone : +352 26970-225
Fax : +352 26970-390
Email : gilles.iserentant@crp-sante.lu
Function : Research Engineer
Phone : +352 26970-337
Fax : +352 26970-390
Email : christine.lambert@crp-sante.lu
Function : Technician
Phone : +352 26970-218
Fax : +352 26970221
Email : morgane.lemaire@crp-sante.lu
Function : Research Engineer
Phone : +352 26970-337
Fax : +352 26970-226
Email : cecile.masquelier@crp-sante.lu
Function : PhD Student
Phone : +352 26970-319
Fax : +352 26970-390
Email : martin.mulinge@crp-sante.lu
Function : Researcher
Phone : +352 26970-318
Fax : +352 26970-390
Function : Research Engineer
Email : arkadiusz.rybicki@crp-sante.lu
Function : PhD Student
Phone : +352 26970-319
Fax : +352 26970-390
Function : Research Engineer
Phone : +352 26970-218
Fax : +352 26970-390
Email : jean-yves.servais@crp-sante.lu
Function : Bioinformatician
Phone : +352 26970-219
Fax : +352 26970-390
Email : daniel.struck@crp-sante.lu
Function : PhD Student
Phone : +352 26970-227
Fax : +352 26970-226
Email : martyna.szpakowska@crp-sante.lu
Function : Bioinformatician
Phone : +352 26970-220
Fax : +352 26970390
Email : anne-marie.ternes@crp-sante.lu
Function : Technician
Phone : +352 26970-212
Fax : +352 26970-390
