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Scope

Our fields of interest range from basic research to contract R&D for the diagnostic and vaccine industry.

  • Immunology and genetic/antigenetic diversity of old and new emerging viruses: relevance for detection, vaccination, pathogenicity, drug resistance, development of new treatment strategies
  • Development of immune-preventive strategies against infectious agents and against environmental risk factors, such as carcinogens.
  • Crosstalk between the immune system and the neuroendocrine system in particular under stress: gene structure, the transcriptional and translational regulation of nuclear receptors, such as the glucocorticoid receptor as the main stress response mediator.
  • Perinatal programming and epigenetics of the immune system.
  • Proteomics studies using 2D DIGE technology paired with MALDI-TOF mass spectrometry and LC-MS in the above areas and other fields in collaboration.

Contact

Department of Immunology
Head of Research Unit: Prof. Dr. Claude P. Muller
Laboratoire National de Santé
20A, rue Auguste Lumière, L-1950 Luxembourg
Tel.: +352 49 06 04 220
Fax: +352 49 06 86
E-mail: claude.muller@crp-sante.lu

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NETWORKS

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The Department of Immunology is a member of several networks including:

  • the VIRIM Network in the Greater Region (SaarLorLux, Wallonie, Rheinland-Pfalz) which has been awarded the Innovation Network Award in 2004
  • the EU COST B28 Action Microrarray technologies for BSL3 and BSL4 Pathogens, of which LNSI is a Workgroup 2 coordinator
  • the WHO Laboratory Network for Measles and Rubella of which our Department is a Regional Reference Laboratory
  • the FluLabNet funded by the EU
  • the International Research Training Group "Psychoneuroendocrinology of Stress - from molecules and genes to affect and cognition", funded by the "Deutsche Forschungsgesellschaft"