Laurent Vallar

Latest publications

Transcriptional variations in the wider peritumoral tissue environment of pancreatic cancer.

  • Bioinformatics and Modelling
  • Genomics Center
October 06, 2017
2017 Oct. Int J Cancer. [Epub ahead of print].
By:
  • Bauer AS
  • Nazarov PV
  • Giese NA
  • Beghelli S
  • Heller A
  • Greenhalf W
  • Costello E
  • Muller A
  • Bier M
  • Strobel O
  • Hackert T
  • Vallar L
  • Scarpa A
  • Buchler MW
  • Neoptolemos JP
  • Kreis S
  • Hoheisel JD.

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

  • NORLUX-Glioma Biology
  • Animal Facility
  • Bioinformatics and Modelling
  • Genomics Center
  • Tumor Microenvironment
September 05, 2017
2017 Sep. Br J Cancer.117(6):813-825. Epub 2017 Aug 10.
By:
  • Abdul Rahim SA
  • Dirkse A
  • Oudin A
  • Schuster A
  • Bohler J
  • Barthelemy V
  • Muller A
  • Vallar L
  • Janji B
  • Golebiewska A
  • Niclou SP.

Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia.

  • Bioinformatics and Modelling
  • Genomics Center
August 01, 2017
2017 Aug. J Pathol.242(4):421-434. Epub 2017 Jul 5.
By:
  • Gauchotte G
  • Hergalant S
  • Vigouroux C
  • Casse JM
  • Houlgatte R
  • Kaoma T
  • Helle D
  • Brochin L
  • Rech F
  • Peyre M
  • Labrousse F
  • Vallar L
  • Gueant JL
  • Vignaud JM
  • Battaglia-Hsu SF.

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

  • Luxembourg Center of Neuropathology
  • Bioinformatics and Modelling
  • Genomics Center
  • NORLUX-Glioma Biology
August 01, 2017
2017 Aug. Int J Oncol.51(2):702-714. Epub 2017 Jun 21.
By:
  • Armento A
  • Ilina EI
  • Kaoma T
  • Muller A
  • Vallar L
  • Niclou SP
  • Kruger MA
  • Mittelbronn M
  • Naumann U.

Chemotherapy resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism.

  • Bioinformatics and Modelling
  • Genomics Center
July 01, 2017
2017 Jul. Cancer Discov.7(7):716-735. Epub 2017 Apr 17.
By:
  • Farge T
  • Saland E
  • de Toni F
  • Aroua N
  • Hosseini M
  • Perry R
  • Bosc C
  • Sugita M
  • Stuani L
  • Fraisse M
  • Scotland S
  • Larrue C
  • Boutzen H
  • Feliu V
  • Nicolau-Travers ML
  • Cassant-Sourdy S
  • Broin N
  • David M
  • Serhan N
  • Sarry A
  • Tavitian S
  • Kaoma T
  • Vallar L
  • Iacovoni J
  • Linares LK
  • Montersino C
  • Castellano R
  • Griessinger E
  • Collette Y
  • Duchamp O
  • Barreira Y
  • Hirsch P
  • Palama T
  • Gales L
  • Delhommeau F
  • Garmy-Susini BH
  • Portais JC
  • Vergez F
  • Selak M
  • Danet-Desnoyers G
  • Carroll M
  • Recher C
  • Sarry JE.

RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples.

  • Bioinformatics and Modelling
  • Genomics Center
  • Discovery Proteomics
June 06, 2017
2017 Jun. BMC Genomics.18(1):443.
By:
  • Nazarov PV
  • Muller A
  • Kaoma T
  • Nicot N
  • Maximo C
  • Birembaut P
  • Tran NL
  • Dittmar G
  • Vallar L.

The angiogenic switch leads to a metabolic shift in human glioblastoma.

  • NORLUX-Glioma Biology
  • Bioinformatics and Modelling
  • Genomics Center
March 01, 2017
2017 Mar. Neuro Oncol.19(3):383-393.
By:
  • Talasila KM
  • Rosland GV
  • Hagland HR
  • Eskilsson E
  • Flones IH
  • Fritah S
  • Azuaje F
  • Atai N
  • Harter PN
  • Mittelbronn M
  • Andersen M
  • Joseph JV
  • Hossain JA
  • Vallar L
  • Noorden CJ
  • Niclou SP
  • Thorsen F
  • Tronstad KJ
  • Tzoulis C
  • Bjerkvig R
  • Miletic H.

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • NORLUX-Glioma Biology
  • In vivo imaging facility
  • Bioinformatics and Modelling
  • Genomics Center
  • National Cytometry Platform
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

  • Bioinformatics and Modelling
  • Genomics Center
  • Clinical Proteomics
  • NORLUX-Glioma Biology
May 31, 2016
2016 May. Sci Rep.6:26822.
By:
  • Rodius S
  • Androsova G
  • Gotz L
  • Liechti R
  • Crespo I
  • Merz S
  • Nazarov PV
  • de Klein N
  • Jeanty C
  • Gonzalez-Rosa JM
  • Muller A
  • Bernardin F
  • Niclou SP
  • Vallar L
  • Mercader N
  • Ibberson M
  • Xenarios I
  • Azuaje F.