Tony Kaoma

Latest publications

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

  • Luxembourg Center of Neuropathology
  • Bioinformatics and Modelling
  • Genomics Center
  • NORLUX-Glioma Biology
August 01, 2017
2017 Aug. Int J Oncol.51(2):702-714. Epub 2017 Jun 21.
By:
  • Armento A
  • Ilina EI
  • Kaoma T
  • Muller A
  • Vallar L
  • Niclou SP
  • Kruger MA
  • Mittelbronn M
  • Naumann U.
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Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia.

  • Bioinformatics and Modelling
  • Genomics Center
August 01, 2017
2017 Aug. J Pathol.242(4):421-434. Epub 2017 Jul 5.
By:
  • Gauchotte G
  • Hergalant S
  • Vigouroux C
  • Casse JM
  • Houlgatte R
  • Kaoma T
  • Helle D
  • Brochin L
  • Rech F
  • Peyre M
  • Labrousse F
  • Vallar L
  • Gueant JL
  • Vignaud JM
  • Battaglia-Hsu SF.
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Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.

  • Bioinformatics and Modelling
  • Genomics Center
July 01, 2017
2017 Jul. Cancer Discov.7(7):716-735. Epub 2017 Apr 17.
By:
  • Farge T
  • Saland E
  • de Toni F
  • Aroua N
  • Hosseini M
  • Perry R
  • Bosc C
  • Sugita M
  • Stuani L
  • Fraisse M
  • Scotland S
  • Larrue C
  • Boutzen H
  • Feliu V
  • Nicolau-Travers ML
  • Cassant-Sourdy S
  • Broin N
  • David M
  • Serhan N
  • Sarry A
  • Tavitian S
  • Kaoma T
  • Vallar L
  • Iacovoni J
  • Linares LK
  • Montersino C
  • Castellano R
  • Griessinger E
  • Collette Y
  • Duchamp O
  • Barreira Y
  • Hirsch P
  • Palama T
  • Gales L
  • Delhommeau F
  • Garmy-Susini BH
  • Portais JC
  • Vergez F
  • Selak M
  • Danet-Desnoyers G
  • Carroll M
  • Recher C
  • Sarry JE.
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RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples.

  • Bioinformatics and Modelling
  • Genomics Center
  • Discovery Proteomics
June 06, 2017
2017 Jun. BMC Genomics.18(1):443.
By:
  • Nazarov PV
  • Muller A
  • Kaoma T
  • Nicot N
  • Maximo C
  • Birembaut P
  • Tran NL
  • Dittmar G
  • Vallar L.
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Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • NORLUX-Glioma Biology
  • In vivo imaging facility
  • Bioinformatics and Modelling
  • Genomics Center
  • National Cytometry Platform
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.
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Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.

  • Genomics Center
April 04, 2016
2016 Apr. J Exp Med.213(4):483-97. Epub 2016 Mar 7.
By:
  • Boutzen H
  • Saland E
  • Larrue C
  • de Toni F
  • Gales L
  • Castelli FA
  • Cathebas M
  • Zaghdoudi S
  • Stuani L
  • Kaoma T
  • Riscal R
  • Yang G
  • Hirsch P
  • David M
  • De Mas-Mansat V
  • Delabesse E
  • Vallar L
  • Delhommeau F
  • Jouanin I
  • Ouerfelli O
  • Le Cam L
  • Linares LK
  • Junot C
  • Portais JC
  • Vergez F
  • Recher C
  • Sarry JE.
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L-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway.

  • Genomics Center
March 01, 2016
2016 Mar. Faseb j.30(3):1218-33. Epub 2015 Nov 30.
By:
  • Lommel MJ
  • Trairatphisan P
  • Gabler K
  • Laurini C
  • Muller A
  • Kaoma T
  • Vallar L
  • Sauter T
  • Schaffner-Reckinger E.
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Assessing cellular and circulating miRNA recovery: the impact of the RNA isolation method and the quantity of input material.

  • Clinical Proteomics
  • Genomics Center
January 20, 2016
2016 Jan. Sci Rep.6:19529.
By:
  • El-Khoury V
  • Pierson S
  • Kaoma T
  • Bernardin F
  • Berchem G.
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Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network.

  • Genomics Center
October 19, 2015
2015 Oct. BMC Genomics.16:809.
By:
  • Pacheco MP
  • John E
  • Kaoma T
  • Heinaniemi M
  • Nicot N
  • Vallar L
  • Bueb JL
  • Sinkkonen L
  • Sauter T.
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Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma.

  • NORLUX-Glioma Biology
  • Genomics Center
May 01, 2015
2015 May. PLoS One.10(5):e0123544.
By:
  • Sanzey M
  • Abdul Rahim SA
  • Oudin A
  • Dirkse A
  • Kaoma T
  • Vallar L
  • Herold-Mende C
  • Bjerkvig R
  • Golebiewska A
  • Niclou SP.
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An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1alpha, IL-1beta, IL-12b, and CCL4 from differentiated HL-60 cells.

  • Genomics Center
March 01, 2015
2015 Mar. J Leukoc Biol.97(3):557-71. Epub 2014 Dec 29.
By:
  • Naegelen I
  • Plancon S
  • Nicot N
  • Kaoma T
  • Muller A
  • Vallar L
  • Tschirhart EJ
  • Brechard S.
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The ROS/SUMO Axis Contributes to the Response of Acute Myeloid Leukemia Cells to Chemotherapeutic Drugs.

  • Genomics Center
June 26, 2014
2014 Jun. Cell Rep.7(6):1815-23. Epub 2014 Jun 5.
By:
  • Bossis G
  • Sarry JE
  • Kifagi C
  • Ristic M
  • Saland E
  • Vergez F
  • Salem T
  • Boutzen H
  • Baik H
  • Brockly F
  • Pelegrin M
  • Kaoma T
  • Vallar L
  • Recher C
  • Manenti S
  • Piechaczyk M.
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Differential effects of antofine N-oxide on solid tumor and leukemia cells.

  • NORLUX-Glioma Biology
  • Genomics Center
June 24, 2014
2014 Jun. Anticancer Agents Med Chem.14(10):1315-23.
By:
  • Bour T
  • Yang X
  • Li W
  • Bernardin F
  • Kaoma T
  • Muller A
  • Vallar L
  • Steinmetz A.
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Neurodegeneration by activation of the microglial complement-phagosome pathway.

  • Genomics Center
June 18, 2014
2014 Jun. J Neurosci.34(25):8546-56.
By:
  • Bodea LG
  • Wang Y
  • Linnartz-Gerlach B
  • Kopatz J
  • Sinkkonen L
  • Musgrove R
  • Kaoma T
  • Muller A
  • Vallar L
  • Di Monte DA
  • Balling R
  • Neumann H.
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The acquisition of resistance to TNFalpha in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray.

  • Tumor Stroma Interactions
  • Tumor Microenvironment
  • Genomics Center
July 01, 2011
2011 Jul. Autophagy.7(7):760-70. Epub 2011 Jul 1.
By:
  • Moussay E
  • Kaoma T
  • Baginska J
  • Muller A
  • Van Moer K
  • Nicot N
  • Nazarov PV
  • Vallar L
  • Chouaib S
  • Berchem G
  • Janji B.
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