Nathalie Grova

Latest publications

Identification of new tetrahydroxylated metabolites of Polycyclic Aromatic Hydrocarbons in hair as biomarkers of exposure and signature of DNA adduct levels.

  • Human Biomonitoring Research Unit
October 12, 2017
2017 Oct. Anal Chim Acta.995:65-76.
By:
  • Grova N
  • Antignac JP
  • Emilie M Hardy EM
  • Fabrice Monteau F
  • Pouponneau K
  • Le Bizec B
  • Appenzeller BM.

Chemical evaluation of electronic cigarettes: Multicomponent analysis of liquid refills and their corresponding aerosols.

  • Human Biomonitoring Research Unit
October 01, 2017
2017 Oct. J Anal Toxicol.41(8):670-678.
By:
  • Beauval N
  • Antherieu S
  • Soyez M
  • Gengler N
  • Grova N
  • Howsam M
  • Hardy EM
  • Fischer M
  • Appenzeller BMR
  • Goossens JF
  • Allorge D
  • Garcon G
  • Lo-Guidice JM
  • Garat A.

Genetic and epigenetic alterations in normal and sensitive COPD-diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived PM2.5.

  • Human Biomonitoring Research Unit
October 01, 2017
2017 Oct. Environ Pollut.230:163-177. Epub 2017 Jun 23.
By:
  • Leclercq B
  • Platel A
  • Antherieu S
  • Alleman LY
  • Hardy EM
  • Perdrix E
  • Grova N
  • Riffault V
  • Appenzeller BM
  • Happillon M
  • Nesslany F
  • Coddeville P
  • Lo-Guidice JM
  • Garcon G.

New insights into urine-based assessment of polycyclic aromatic hydrocarbon-exposure from a rat model: Identification of relevant metabolites and influence of elimination kinetics.

  • Human Biomonitoring Research Unit
September 01, 2017
2017 Sep. Environ Pollut.228:484-495. Epub 2017 May 30.
By:
  • Grova N
  • Fays F
  • Hardy EM
  • Appenzeller BMR.

Hair analysis for the biomonitoring of pesticide exposure: comparison with blood and urine in a rat model.

  • Human Biomonitoring Research Unit
  • Competence Center for Methodology and Statistics
August 01, 2017
2017 Aug. Arch Toxicol.91(8):2813-2825. Epub 2016 Dec 23.
By:
  • Appenzeller BMR
  • Hardy EM
  • Grova N
  • Chata C
  • Fays F
  • Briand O
  • Schroeder H
  • Duca RC.

Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

  • Human Biomonitoring Research Unit
March 15, 2017
2017 Mar. Sci Rep.7(1):195.
By:
  • Hardonniere K
  • Fernier M
  • Gallais I
  • Mograbi B
  • Podechard N
  • Le Ferrec E
  • Grova N
  • Appenzeller B
  • Burel A
  • Chevanne M
  • Sergent O
  • Huc L
  • Bortoli S
  • Lagadic-Gossmann D.

Differential responses of healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived PM4.

  • Human Biomonitoring Research Unit
November 01, 2016
2016 Nov. Environ Pollut.218:1074-1088. Epub 2016 Sep 1.
By:
  • Leclercq B
  • Happillon M
  • Antherieu S
  • Hardy EM
  • Alleman LY
  • Grova N
  • Perdrix E
  • Appenzeller BM
  • Lo Guidice JM
  • Coddeville P
  • Garcon G.

Determination of tetrahydroxylated metabolites in hair and DNA of rats under controlled exposure to a mixture of Polycyclic Aromatic Hydrocarbons: new biomarkers for assessing human exposure.

  • Human Biomonitoring Research Unit
  • Competence Center for Methodology and Statistics
June 01, 2016
2016 Jun. Proceeding Organohalogen Compounds Database.78:445-447.
By:
  • Grova N
  • Hardy EM
  • Fays F
  • Appenzeller BM.

Epigenetic changes upon multi-residue exposure to polycyclic aromatic hydrocarbons.

  • Human Biomonitoring Research Unit
June 01, 2016
2016 Jun. Proceeding Organohalogen Compounds Database.78:845-847.
By:
  • Duca R
  • Grova N
  • Ghosh M
  • Appenzeller BM
  • Vanoirbeek J
  • Godderis L.

Influence of pesticide physicochemical properties on the association between plasma and hair concentration.

  • Human Biomonitoring Research Unit
May 01, 2016
2016 May. Anal Bioanal Chem.408(13):3601-12. Epub 2016 Mar 11.
By:
  • Chata C
  • Hardy EM
  • Grova N
  • Appenzeller BM.

Analysis of tetrahydroxylated benzo[a]pyrene isomers in hair as biomarkers of exposure to benzo[a]pyrene.

  • Human Biomonitoring Research Unit
March 01, 2016
2016 Mar. Anal Bioanal Chem.408(8):1997-2008. Epub 2016 Feb 3.
By:
  • Grova N
  • Hardy EM
  • Meyer P
  • Appenzeller BM.

TETROLS, Detection of Tetrols of polycyclic aromatic hydrocarbons in hair as biomarkers of exposure and signature of DNA-adduct level, Funding: ADEME project 2014-2015: Final report. (Book)

  • Human Biomonitoring Research Unit
March 01, 2016
2016 Mar. Angers: ADEME, 2017. In press
By:
  • Grova N
  • Antignac JP
  • Lebizec B
  • Appenzeller BM.

Behavioral toxicity and physiological changes from repeated exposure to fluorene administered orally or intraperitoneally to adult male Wistar rats: A dose-response study.

  • Human Biomonitoring Research Unit
March 01, 2016
2016 Mar. Neurotoxicology.53:321-33. Epub 2015 Nov 23.
By:
  • Peiffer J
  • Grova N
  • Hidalgo S
  • Salquebre G
  • Rychen G
  • Bisson JF
  • Appenzeller BM
  • Schroeder H.

Tetrahydroxylated-benzo[a]pyrene isomer analysis after hydrolysis of DNA-adducts isolated from rat and human white blood cells.

  • Human Biomonitoring Research Unit
September 17, 2014
2014 Sep. J Chromatogr A.1364:183-91. Epub 2014 Sep 6.
By:
  • Grova N
  • Salquebre G
  • Hardy EM
  • Schroeder H
  • Appenzeller BM.

Inhibitory action of benzo[alpha]pyrene on hepatic lipoprotein receptors in vitro and on liver lipid homeostasis in mice.

  • Human Biomonitoring Research Unit
July 23, 2014
2014 Jul. PLoS One.9(7):e102991.
By:
  • Layeghkhavidaki H
  • Lanhers MC
  • Akbar S
  • Gregory-Pauron L
  • Oster T
  • Grova N
  • Appenzeller B
  • Jasniewski J
  • Feidt C
  • Corbier C
  • Yen FT.

Short-term effects of a perinatal exposure to a 16 Polycyclic Aromatic Hydrocarbon mixture in rats: Assessment of early motor and sensorial development and cerebral cytochrome oxidase activity in pups.

  • Human Biomonitoring Research Unit
July 01, 2014
2014 Jul. Neurotoxicology.43:90-101. Epub 2014 Apr 4.
By:
  • Crepeaux G
  • Grova N
  • Bouillaud-Kremarik P
  • Sikhayeva N
  • Salquebre G
  • Rychen G
  • Soulimani R
  • Appenzeller B
  • Schroeder H.

Gas chromatography-tandem mass spectrometry analysis of 52 monohydroxylated metabolites of polycyclic aromatic hydrocarbons in hairs of rats after controlled exposure.

  • Human Biomonitoring Research Unit
November 01, 2013
2013 Nov. Anal Bioanal Chem.405(27):8897-911. Epub 2013 Sep 7.
By:
  • Grova N
  • Salquebre G
  • Appenzeller BM.

Neurobehavioral toxicity of a repeated exposure (14 days) to the airborne polycyclic aromatic hydrocarbon fluorene in adult wistar male rats.

  • Human Biomonitoring Research Unit
August 20, 2013
2013 Aug. PLoS One.8(8):e71413.
By:
  • Peiffer J
  • Cosnier F
  • Grova N
  • Nunge H
  • Salquebre G
  • Decret MJ
  • Cossec B
  • Rychen G
  • Appenzeller BM
  • Schroeder H.

Determination of PAHs and OH-PAHs in rat brain by gas chromatography tandem (triple quadrupole) mass spectrometry.

  • Human Biomonitoring Research Unit
October 17, 2011
2011 Oct. Chem Res Toxicol.24(10):1653-67. Epub 2011 Oct 3.
By:
  • Grova N
  • Salquebre G
  • Schroeder H
  • Appenzeller BM.