Bassam Janji

Latest publications

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.

  • Tumor Microenvironment
  • NORLUX-Glioma Biology
October 05, 2018
2018 Oct. Int J Cancer. [Epub ahead of print].
By:
  • Johannessen TA
  • Hasan-Olive MAM
  • Zhu H
  • Denisova O
  • Grudic A
  • Latif M
  • Saed H
  • Varughese JK
  • Rosland GV
  • Yang N
  • Sundstrom T
  • Nordal A
  • Tronstad KJ
  • Wang J
  • Lund-Johansen M
  • Simonsen A
  • Janji B
  • Westermarck J
  • Bjerkvig R
  • Prestegarden L.

Driving cytotoxic natural killer cells into melanoma: If CCL5 plays the music, autophagy calls the shots.

  • Tumor Microenvironment
  • Immuno-Pharmacology and Interactomics
  • Allergy and Clinical Immunology
September 11, 2018
2018 Sep. Crit Rev Oncog.23(5-6). In press.
By:
  • Xiao M
  • Noman MZ
  • Menard L
  • Chevigne A
  • Szpakowska M
  • Bosseler M
  • Ollert M
  • Berchem G
  • Janji B.

Actin cytoskeleton remodeling drives breast cancer cell escape from natural killer-mediated cytotoxicity.

  • Cytoskeleton and Cancer Progression
  • National Cytometry Platform
  • NORLUX-Glioma Biology
  • Tumor Microenvironment
August 13, 2018
2018 Aug. Cancer Res. [Epub ahead of print].
By:
  • Al Absi A
  • Wurzer H
  • Guerin CL
  • Hoffmann C
  • Moreau F
  • Mao X
  • Brown-Clay J
  • Petrolli R
  • Pou Casellas C
  • Dieterle M
  • Thiery JP
  • Chouaib S
  • Berchem G
  • Janji B
  • Thomas C.

Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2.

  • Cytoskeleton and Cancer Progression
  • Tumor Microenvironment
July 05, 2018
2018 Jul. Sci Rep.8(1):10191.
By:
  • Hoffmann C
  • Mao X
  • Brown-Clay J
  • Moreau F
  • Al Absi A
  • Wurzer H
  • Sousa B
  • Schmitt F
  • Berchem G
  • Janji B
  • Thomas C.

High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Tumor Microenvironment
May 24, 2018
2018 May. OncoImmunology.7(8):e1465167.
By:
  • Wierz M
  • Janji B
  • Berchem G
  • Moussay E
  • Paggetti J.

Inhibition of HIF1alpha-dependent upregulation of Phospho-l-Plastin resensitizes multiple myeloma cells to frontline therapy.

  • Tumor Microenvironment
  • Bioinformatics and Modelling
  • Laboratory of Oncolytic-Virus-Immuno-Therapeutics
May 23, 2018
2018 May. Int J Mol Sci.19(6):1551.
By:
  • Bosseler M
  • Marani V
  • Broukou A
  • Lequeux A
  • Kaoma T
  • Schlesser V
  • François J-H
  • Palissot V
  • Berchem G
  • Aouali N
  • Janji B.

Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
April 25, 2018
2018 Apr. OncoImmunology.7(8):e1452583.
By:
  • Noman MZ
  • Paggetti J
  • Moussay E
  • Berchem G
  • Janji B.

Targeting autophagy in the tumor microenvironment: New challenges and opportunities for regulating tumor immunity.

  • Tumor Microenvironment
April 25, 2018
2018 Apr. Front Immunol.9:887.
By:
  • Janji B
  • Berchem G
  • Chouaib S.

Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • National Cytometry Platform
  • Tumor Microenvironment
  • NORLUX-Glioma Biology
  • Allergy and Clinical Immunology
April 05, 2018
2018 Apr. Blood.131(14):1617-1621. Epub 2018 Feb 13.
By:
  • Wierz M
  • Pierson S
  • Guyonnet L
  • Viry E
  • Lequeux A
  • Oudin A
  • Niclou SP
  • Ollert M
  • Berchem G
  • Janji B
  • Guerin C
  • Paggetti J
  • Moussay E.

Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield.

  • Tumor Microenvironment
March 11, 2018
2018 Mar. Autophagy.14(4):730-732. Epub 2018 Mar 11.
By:
  • Noman MZ
  • Berchem G
  • Janji B.

CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT.

  • Tumor Microenvironment
  • Bioinformatics and Modelling
February 15, 2018
2018 Feb. OncoImmunology.7(4):e1345415. In press.
By:
  • Noman MZ
  • Van Moer K
  • Marani V
  • Gemmill RM
  • Tranchevent LC
  • Azuaje F
  • Muller A
  • Chouaib S
  • Thiery JP
  • Berchem G
  • Janji B.

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
  • National Cytometry Platform
October 31, 2017
2017 Oct. Proc Natl Acad Sci U S A.114(44):E9271-E9279. Epub 2017 Oct 16.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Noman MZ
  • Viry E
  • Moussay E
  • Van Moer K
  • Kreis S
  • Guerin C
  • Buart S
  • Robert C
  • Borg C
  • Vielh P
  • Chouaib S
  • Berchem G
  • Janji B.

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

  • NORLUX-Glioma Biology
  • Animal Facility
  • Bioinformatics and Modelling
  • Genomics Center
  • Tumor Microenvironment
September 05, 2017
2017 Sep. Br J Cancer.117(6):813-825. Epub 2017 Aug 10.
By:
  • Abdul Rahim SA
  • Dirkse A
  • Oudin A
  • Schuster A
  • Bohler J
  • Barthelemy V
  • Muller A
  • Vallar L
  • Janji B
  • Golebiewska A
  • Niclou SP.

Human CD56dimCD16dim cells as an individualized Natural Killer cell subset.

  • HIV Clinical and Translational Research
  • Innate Cellular Immunity and Chronic Inflammation
  • Competence Center for Methodology and Statistics
  • Tumor Microenvironment
June 19, 2017
2017 Jun. Front Immunol.8:699.
By:
  • Amand M
  • Iserentant G
  • Poli A
  • Sleiman M
  • Fievez V
  • Sanchez IP
  • Sauvageot N
  • Michel T
  • Aouali N
  • Janji B
  • Trujillo-Vargas CM
  • Seguin-Devaux C
  • Zimmer J.

Activation of NK cells and disruption of PD-L1/PD-1 axis: two different ways for lenalidomide to block myeloma progression.

  • Tumor Microenvironment
April 04, 2017
2017 Apr. Oncotarget.8(14):24031-24044.
By:
  • Giuliani M
  • Janji B
  • Berchem G.

Cutting edge: NANOG activates autophagy under hypoxic stress by binding to BNIP3L promoter.

  • Tumor Microenvironment
February 15, 2017
2017 Feb. J Immunol.198(4):1423-1428. Epub 2017 Jan 16.
By:
  • Hasmim M
  • Janji B
  • Khaled M
  • Noman MZ
  • Louache F
  • Bordereaux D
  • Abderamane A
  • Baud V
  • Mami-Chouaib F
  • Chouaib S.

The critical role of hypoxia in tumor-mediated immunosuppression. In Hypoxia and Human Diseases. (Book Chapter)

  • Tumor Microenvironment
February 01, 2017
2017 Feb. Zheng J, ed. Intech, 2017. p.349-364. ISBN 978-953-51-2895-3.
By:
  • Aouali N
  • Bosseler M
  • Sauvage D
  • Van Moer K
  • Berchem G
  • Janji B.

The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200.

  • Tumor Microenvironment
January 23, 2017
2017 Jan. OncoImmunology.6(1):e1263412.
By:
  • Noman MZ
  • Janji B
  • Abdou A
  • Hasmim M
  • Terry S
  • Tan TZ
  • Mami-Chouaib F
  • Thiery JP
  • Chouaib S.

Hijacker of the antitumor immune response: autophagy is showing its worst facet.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
November 18, 2016
2016 Nov. Front Oncol.6(246).
By:
  • Viry E
  • Noman MZ
  • Arakelian T
  • Lequeux A
  • Chouaib S
  • Berchem G
  • Moussay E
  • Paggetti J
  • Janji B.

Renal cell carcinoma programmed death-ligand 1, a new direct target of hypoxia-inducible factor-2 alpha, is regulated by von Hippel-Lindau gene mutation status.

  • Tumor Microenvironment
October 01, 2016
2016 Oct. Eur Urol.70(4):623-632. Epub 2015 Dec 23.
By:
  • Messai Y
  • Gad S
  • Noman MZ
  • Le Teuff G
  • Couve S
  • Janji B
  • Kammerer SF
  • Rioux-Leclerc N
  • Hasmim M
  • Ferlicot S
  • Baud V
  • Mejean A
  • Mole DR
  • Richard S
  • Eggermont AM
  • Albiges L
  • Mami-Chouaib F
  • Escudier B
  • Chouaib S.