Jérôme Paggetti

Latest publications

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
  • National Cytometry Platform
October 31, 2017
2017 Oct. Proc Natl Acad Sci U S A.114(44):E9271-E9279. Epub 2017 Oct 16.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Noman MZ
  • Viry E
  • Moussay E
  • Van Moer K
  • Kreis S
  • Guerin C
  • Buart S
  • Robert C
  • Borg C
  • Vielh P
  • Chouaib S
  • Berchem G
  • Janji B.

Tumor-derived exosomes modulate PD-L1 expression in monocytes.

  • Tumor Stroma Interactions
July 28, 2017
2017 Jul. Sci Immunol.2(13):pii: eaah5509.
By:
  • Haderk F
  • Schulz R
  • Iskar M
  • Cid LL
  • Worst T
  • Willmund KV
  • Schulz A
  • Warnken U
  • Seiler J
  • Benner A
  • Nessling M
  • Zenz T
  • Gobel M
  • Durig J
  • Diederichs S
  • Paggetti J
  • Moussay E
  • Stilgenbauer S
  • Zapatka M
  • Lichter P
  • Seiffert M.

Hijacker of the antitumor immune response: autophagy is showing its worst facet.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
November 18, 2016
2016 Nov. Front Oncol.6(246).
By:
  • Viry E
  • Noman MZ
  • Arakelian T
  • Lequeux A
  • Chouaib S
  • Berchem G
  • Moussay E
  • Paggetti J
  • Janji B.

The multifaceted role of autophagy in tumor evasion from immune surveillance.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
April 05, 2016
2016 Apr. Oncotarget.7(14):17591-607.
By:
  • Janji B
  • Viry E
  • Moussay E
  • Paggetti J
  • Arakelian T
  • Mgrditchian T
  • Messai Y
  • Noman MZ
  • Van Moer K
  • Hasmim M
  • Mami-Chouaib F
  • Berchem G
  • Chouaib S.

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-beta and miR23a transfer.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
April 01, 2016
2016 Apr. OncoImmunology.5(4):e1062968. Epub 2015 Jun 24.
By:
  • Berchem G
  • Noman MZ
  • Bosseler M
  • Paggetti J
  • Baconnais S
  • Le Cam E
  • Nanbakhsh A
  • Moussay E
  • Mami-Chouaib F
  • Janji B
  • Chouaib S.

BCR engagement in CLL: when translation goes wrong.

  • Tumor Stroma Interactions
January 28, 2016
2016 Jan. Blood.127(4):378-80.
By:
  • Paggetti J
  • Moussay E.

Autophagy regulation of the tumor immunity: An old housekeeper for a new function. In Cell Death - Autophagy, Necrosis and Apoptosis. (Book Chapter)

  • Tumor Microenvironment
  • Tumor Stroma Interactions
December 16, 2015
2015 Dec. Ntuli DT, ed. Rijeka: InTech, 2015. p.37-61. ISBN 978-953-51-2236-4.
By:
  • Arakelian T
  • Mgrditchian T
  • Viry E
  • Van Moer K
  • Paggetti J
  • Berchem G
  • Chouaib S
  • Janji B.

Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.

  • Tumor Stroma Interactions
  • Tumor Microenvironment
  • Discovery Proteomics
  • Clinical Proteomics
August 27, 2015
2015 Aug. Blood.126(9):1106-17. Epub 2015 Jun 22.
By:
  • Paggetti J
  • Haderk F
  • Seiffert M
  • Janji B
  • Distler U
  • Ammerlaan W
  • Kim YJ
  • Adam J
  • Lichter P
  • Solary E
  • Berchem G
  • Moussay E.

Hypoxia: A key feature of the tumor microenvironment triggers several mechanisms of evasion from natural killer and cytotoxic T lymphocytes surveillance.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
  • Cytoskeleton and Cancer Progression
November 20, 2014
2014 Nov. J Imm Res.1(2):7.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Viry E
  • Al-Absi A
  • Medves S
  • Moussay E
  • Berchem G
  • Thomas C
  • Janji B.

Autophagy: An adaptive metabolic response to stress shaping the antitumor immunity.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
November 01, 2014
2014 Nov. Biochem Pharmacol.92(1):31-42. Epub 2014 Jul 17.
By:
  • Viry E
  • Paggetti J
  • Baginska J
  • Mgrditchian T
  • Berchem G
  • Moussay E
  • Janji B.

Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy.

  • Tumor Stroma Interactions
  • Tumor Microenvironment
September 14, 2014
2014 Sep. Cancer Cell Microenviron.1(4):e213.
By:
  • Paggetti J
  • Viry E
  • Berchem G
  • Moussay E
  • Janji B.

Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells.

  • Tumor Stroma Interactions
December 01, 2013
2013 Dec. Biochim Biophys Acta-Mol Cell Res.1833(12):3054-3063. Epub 2013 Aug 27.
By:
  • Largeot A
  • Paggetti J
  • Broseus J
  • Aucagne R
  • Lagrange B
  • Martin RZ
  • Berthelet J
  • Quere R
  • Lucchi G
  • Ducoroy P
  • Bastie JN
  • Delva L.

The Critical Role of the Tumor Microenvironment in Shaping Natural Killer Cell-Mediated Anti-Tumor Immunity.

  • Tumor Microenvironment
  • Tumor Stroma Interactions
December 01, 2013
2013 Dec. Front Immunol.4:490.
By:
  • Baginska J
  • Viry E
  • Paggetti J
  • Medves S
  • Berchem G
  • Moussay E
  • Janji B.

Stromal cell-induced miRNA alteration in chronic lymphocytic leukemia: how a minute and unavoidable cell contamination impairs miRNA profiling.

  • Tumor Stroma Interactions
August 01, 2013
2013 Aug. Leukemia.27(8):1773-6. Epub 2013 Feb 14.
By:
  • Paggetti J
  • Berchem G
  • Moussay E.

MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Tumor Microenvironment
  • Genomics Center
April 19, 2011
2011 Apr. Proc Natl Acad Sci U S A.108(16):6573-8. Epub 2011 Apr 1.
By:
  • Moussay E
  • Wang K
  • Cho JH
  • van Moer K
  • Pierson S
  • Paggetti J
  • Nazarov PV
  • Palissot V
  • Hood LE
  • Berchem G
  • Galas DJ.