Fred Fack

Latest publications

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

  • NORLUX-Glioma Biology
  • In vivo imaging facility
  • Bioinformatics and Modelling
October 20, 2017
2017 Oct. EMBO Mol Med. [Epub ahead of print].
By:
  • Fack F
  • Tardito S
  • Hochart G
  • Oudin A
  • Zheng L
  • Fritah S
  • Golebiewska A
  • Nazarov PV
  • Bernard A
  • Hau AC
  • Keunen O
  • Leenders W
  • Lund-Johansen M
  • Stauber J
  • Gottlieb E
  • Bjerkvig R
  • Niclou SP.

Targeted proteomics to assess the response to anti-angiogenic treatment in human glioblastoma (GBM).

  • NORLUX-Glioma Biology
  • Discovery Proteomics
February 01, 2016
2016 Feb. Mol Cell Proteomics.15(2):481-92. Epub 2015 Aug 4.
By:
  • Demeure K
  • Fack F
  • Duriez E
  • Tiemann K
  • Bernard A
  • Golebiewska A
  • Bougnaud S
  • Bjerkvig R
  • Domon B
  • Niclou SP.

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

  • NORLUX-Glioma Biology
  • In vivo imaging facility
December 01, 2015
2015 Dec. Nat Cell Biol.17(12):1556-68. Epub 2015 Nov 23.
By:
  • Tardito S
  • Oudin A
  • Ahmed SU
  • Fack F
  • Keunen O
  • Zheng L
  • Miletic H
  • Sakariassen PO
  • Weinstock A
  • Wagner A
  • Lindsay SL
  • Hock AK
  • Barnett SC
  • Ruppin E
  • Morkve SH
  • Lund-Johansen M
  • Chalmers AJ
  • Bjerkvig R
  • Niclou SP
  • Gottlieb E.

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.

  • NORLUX-Glioma Biology
  • In vivo imaging facility
January 01, 2015
2015 Jan. Acta Neuropathol.129(1):115-31. Epub 2014 Oct 17.
By:
  • Fack F
  • Espedal H
  • Keunen O
  • Golebiewska A
  • Obad N
  • Harter PN
  • Mittelbronn M
  • Bahr O
  • Weyerbrock A
  • Stuhr L
  • Miletic H
  • Sakariassen PO
  • Stieber D
  • Rygh CB
  • Lund-Johansen M
  • Zheng L
  • Gottlieb E
  • Niclou SP
  • Bjerkvig R.

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture.

  • NORLUX-Glioma Biology
July 11, 2014
2014 Jul. Proteome Sci.12:39.
By:
  • Rajcevic U
  • Knol JC
  • Piersma S
  • Bougnaud S
  • Fack F
  • Sundlisaeter E
  • Sondenaa K
  • Myklebust R
  • Pham TV
  • Niclou SP
  • Jimenez CR.

The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.

  • NORLUX-Glioma Biology
September 01, 2013
2013 Sep. Neuro Oncol.15(9):1200-11. Epub 2013 May 30.
By:
  • Johansson M
  • Oudin A
  • Tiemann K
  • Bernard A
  • Golebiewska A
  • Keunen O
  • Fack F
  • Stieber D
  • Wang B
  • Hedman H
  • Niclou SP.

Combined effect of tissue stabilization and protein extraction methods on phosphoprotein analysis.

  • NORLUX-Glioma Biology
June 01, 2013
2013 Jun. Biopreserv Biobank.11(3):161-165.
By:
  • Kofanova OA
  • Fack F
  • Niclou SP
  • Betsou F.

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

  • NORLUX-Glioma Biology
May 29, 2013
2013 May. Acta Neuropathol Commun.1:18.
By:
  • Navis AC
  • Niclou SP
  • Fack F
  • Stieber D
  • van Lith S
  • Verrijp K
  • Wright A
  • Stauber J
  • Tops B
  • Otte-Holler I.

Detection of differentially modified pathogen proteins by western blot after 2D Gel electrophoresis and identification by MALDI-TOF/TOF. In BSL3 and BSL4 Agents: Proteomics, Glycomics, and Antigenicity. (Book Chapter)

  • NORLUX-Glioma Biology
  • National Cytometry Platform
  • Vaccinology and B Cell Immunology
September 30, 2011
2011 Sep. Stulik J, Toman R, Butaye P and Ulrich RG, eds. Weinheim: Wiley-VCH Verlag, 2011. p.131-138. ISBN 9783527327805.
By:
  • Fack F
  • Kessler JR
  • Pirrotte P
  • Kremer JR
  • Revets D
  • Ammerlaan W
  • Muller CP.

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma.

  • NORLUX-Glioma Biology
March 01, 2011
2011 Mar. Proc Natl Acad Sci U S A.108(9):3749-54. Epub 2011 Feb 14.
By:
  • Keunen O
  • Johansson M
  • Oudin A
  • Sanzey M
  • Rahim SA
  • Fack F
  • Thorsen F
  • Taxt T
  • Bartos M
  • Jirik R
  • Miletic H
  • Wang J
  • Stieber D
  • Stuhr L
  • Moen I
  • Rygh CB
  • Bjerkvig R
  • Niclou SP.

Glioma proteomics: Status and perspectives.

  • NORLUX-Glioma Biology
September 10, 2010
2010 Sep. J Proteomics.73(10):1823-38. Epub 2010 Mar 20.
By:
  • Niclou SP
  • Fack F
  • Rajcevic U.