Laurent Vallar

Latest publications

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

  • NORLUX-Glioma Biology
  • Animal Facility
  • Bioinformatics and Modelling
  • Genomics Center
  • Tumor Microenvironment
September 05, 2017
2017 Sep. Br J Cancer.117(6):813-825. Epub 2017 Aug 10.
By:
  • Abdul Rahim SA
  • Dirkse A
  • Oudin A
  • Schuster A
  • Bohler J
  • Barthelemy V
  • Muller A
  • Vallar L
  • Janji B
  • Golebiewska A
  • Niclou SP.

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

  • Luxembourg Center of Neuropathology
  • Bioinformatics and Modelling
  • Genomics Center
  • NORLUX-Glioma Biology
August 01, 2017
2017 Aug. Int J Oncol.51(2):702-714. Epub 2017 Jun 21.
By:
  • Armento A
  • Ilina EI
  • Kaoma T
  • Muller A
  • Vallar L
  • Niclou SP
  • Kruger MA
  • Mittelbronn M
  • Naumann U.

The angiogenic switch leads to a metabolic shift in human glioblastoma.

  • NORLUX-Glioma Biology
  • Bioinformatics and Modelling
  • Genomics Center
March 01, 2017
2017 Mar. Neuro Oncol.19(3):383-393.
By:
  • Talasila KM
  • Rosland GV
  • Hagland HR
  • Eskilsson E
  • Flones IH
  • Fritah S
  • Azuaje F
  • Atai N
  • Harter PN
  • Mittelbronn M
  • Andersen M
  • Joseph JV
  • Hossain JA
  • Vallar L
  • Noorden CJ
  • Niclou SP
  • Thorsen F
  • Tronstad KJ
  • Tzoulis C
  • Bjerkvig R
  • Miletic H.

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • NORLUX-Glioma Biology
  • In vivo imaging facility
  • Bioinformatics and Modelling
  • Genomics Center
  • National Cytometry Platform
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

  • Bioinformatics and Modelling
  • Genomics Center
  • Clinical Proteomics
  • NORLUX-Glioma Biology
May 31, 2016
2016 May. Sci Rep.6:26822.
By:
  • Rodius S
  • Androsova G
  • Gotz L
  • Liechti R
  • Crespo I
  • Merz S
  • Nazarov PV
  • de Klein N
  • Jeanty C
  • Gonzalez-Rosa JM
  • Muller A
  • Bernardin F
  • Niclou SP
  • Vallar L
  • Mercader N
  • Ibberson M
  • Xenarios I
  • Azuaje F.

Gene regulatory network inference of Immunoresponsive Gene 1 (IRG1) identifies Interferon Regulatory Factor 1 (IRF1) as its transcriptional regulator in mammalian macrophages.

  • NORLUX-Glioma Biology
  • Genomics Center
February 12, 2016
2016 Feb. PLoS One.11(2):e0149050.
By:
  • Tallam A
  • Perumal TM
  • Antony PM
  • Jager C
  • Fritz JV
  • Vallar L
  • Balling R
  • Del Sol A
  • Michelucci A.

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma.

  • NORLUX-Glioma Biology
  • Genomics Center
May 01, 2015
2015 May. PLoS One.10(5):e0123544.
By:
  • Sanzey M
  • Abdul Rahim SA
  • Oudin A
  • Dirkse A
  • Kaoma T
  • Vallar L
  • Herold-Mende C
  • Bjerkvig R
  • Golebiewska A
  • Niclou SP.

Differential effects of antofine N-oxide on solid tumor and leukemia cells.

  • NORLUX-Glioma Biology
  • Genomics Center
June 24, 2014
2014 Jun. Anticancer Agents Med Chem.14(10):1315-23.
By:
  • Bour T
  • Yang X
  • Li W
  • Bernardin F
  • Kaoma T
  • Muller A
  • Vallar L
  • Steinmetz A.

Bronchial airway gene expression in smokers with lung or head and neck cancer.

  • NORLUX-Glioma Biology
  • Genomics Center
  • Tumor Microenvironment
April 01, 2014
2014 Apr. Cancer Med.3(2):322-36. Epub 2014 Feb 4.
By:
  • Van Dyck E
  • Nazarov PV
  • Muller A
  • Nicot N
  • Bosseler M
  • Pierson S
  • Van Moer K
  • Palissot V
  • Mascaux C
  • Knolle U
  • Ninane V
  • Nati R
  • Bremnes RM
  • Vallar L
  • Berchem G
  • Schlesser M.

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

  • NORLUX-Glioma Biology
  • National Cytometry Platform
  • Genomics Center
February 01, 2014
2014 Feb. Acta Neuropathol.127(2):203-1. Epub 2013 Oct 24.
By:
  • Stieber D
  • Golebiewska A
  • Evers L
  • Lenkiewicz E
  • Brons NH
  • Nicot N
  • Oudin A
  • Bougnaud S
  • Hertel F
  • Bjerkvig R
  • Vallar L
  • Barrett MT
  • Niclou SP.

Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells.

  • NORLUX-Glioma Biology
  • National Cytometry Platform
  • Genomics Center
May 01, 2013
2013 May. Brain.136(Pt 5):1462-75. Epub 2013 Mar 4.
By:
  • Golebiewska A
  • Bougnaud S
  • Stieber D
  • Brons NH
  • Vallar L
  • Hertel F
  • Klink B
  • Schrock E
  • Bjerkvig R
  • Niclou SP.